What exactly are you speaking about? The VB code that is used by IIS when running an ASP script is server-side only. It matters not one wit what the client browser is. The only thing that matters is the scripting language used within the actual HTML (as it is seen on the client's side)
For instance:
http://www.evolutionsoftwarellc.com/scs/index.asp
navigate to my website using IE, Netscape, and Firefox (or anyother browser for that matter, on any machine) and it looks and works the same. Why? because I only use JavaScript on the client side, but I use ASP (read Visual Basic) on the server side.
So unless you have foolishly added an html tag that says:
<script langauge="VBScript">
</script>
instead of
<script langauge="JavaScript">
</script>
then you have nothing to be concerned about.
Chi