<asp:datagrid id=viewRequestDG runat="server" Width="100%" AutoGenerateColumns="False" DataMember="ShowRequest" DataSource="<%# viewRequestDS1 %>" OnEditCommand="EditClick" OnDeleteCommand="DeleteClick" OnUpdateCommand="SaveClick" OnCancelCommand="CancelClick"> 

... 

<EditItemTemplate> 
<asp:DropDownList id=ddlStatus DataSource="<%# PopulateList() %>" Runat="server"> 
</asp:DropDownList> 
</EditItemTemplate>

public void SaveClick(object sender, DataGridCommandEventArgs e) 
{ 
DropDownList ddl = (DropDownList)e.Item.Cells[6].FindControl("ddlStatus"); 
DataRow row = viewRequestDS1.Tables["Request"].Rows[e.Item.ItemIndex]; 
row.ItemArray.SetValue(ddl.SelectedItem.Value.ToString(),7); 
//row.ItemArray[7] = ddl.SelectedItem.Value.ToString(); 
RequestDA.Update(viewRequestDS1,"Request"); 
viewRequestDG.EditItemIndex = -1; 
UpdateViewRequestDG(); 


} 

public void EditClick(object sender, DataGridCommandEventArgs e) 
{ 

viewRequestDG.EditItemIndex = e.Item.ItemIndex; 
viewRequestDG.DataBind(); 

} 

public string[] PopulateList() 
{ 
string[] status = {"Hold", "Declined", "Accepted", "Paid"}; 
return status; 
}